Senior Associate Scientist Molecular Biology, Discovery Cardiovascular

$83,000 - $104,000/Yr

Bristol-Myers Squibb - Brisbane, CA

Full-time - Mid Level

Hybrid - Brisbane, CA

Chemical Manufacturing

About the position

The Senior Associate Scientist in Molecular Biology at Bristol Myers Squibb will play a crucial role in the Cardiovascular Discovery Biology team, focusing on the discovery and development of novel therapies for serious cardiovascular diseases. This position involves collaboration with various teams to establish and validate cellular models and develop high-throughput screening assays, contributing to the advancement of transformative medicines.

Responsibilities

• Perform standard cell culture support including maintenance and cardiogenic differentiation of iPSC lines.
• Support iPSC-CM differentiation and manufacturing towards generating disease models and supporting screening campaigns.
• Utilize a broad range of molecular and cellular biology methods to interrogate and validate iPSC disease models and novel therapeutic targets/hypotheses.
• Collaborate with discovery biology and LDO teams to develop and optimize HTS cell-based biological and validation assays.
• Support gene-editing of mammalian cells, including iPSCs, towards generating disease models.
• Prepare reports, publications and present to senior management and cross-functional teams.
• Support some lab management duties as assigned.

Requirements

• Bachelor's Degree with 4+ years of industry experience or a Master's Degree with 2+ years of industry experience.
• Extensive hands-on experience in cell biology and cellular assays including iPSC line maintenance and cardiogenic differentiation.
• Strong experience with cellular and molecular biology methodologies including cytotoxicity assays, gene expression analysis, RNAi technologies and immunocytochemistry.
• Hands-on experience with methodologies for functional assessment of iPSC-CMs (contractility, electrophysiology, metabolic properties).
• Experience with CRISPR/Cas9 gene editing technologies.

Nice-to-haves

• Experience with cell line engineering and HTS screening methodologies.

Benefits

• Medical, pharmacy, dental and vision care.
• Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP).
• Financial well-being resources and a 401(K).
• Short- and long-term disability insurance.
• Life insurance and supplemental health insurance.
• Business travel protection and survivor support.
• Paid national holidays and optional holidays.
• Global Shutdown Days between Christmas and New Year's holiday.
• Up to 120 hours of paid vacation.
• Up to two (2) paid days to volunteer.
• Sick time off and summer hours flexibility.
• Parental, caregiver, bereavement, and military leave.
• Family care services such as adoption and surrogacy reimbursement, fertility/infertility benefits, support for traveling mothers, and child, elder and pet care resources.
• Tuition reimbursement and a recognition program.