The Chan Zuckerberg Initiative was founded by Priscilla Chan and Mark Zuckerberg in 2015 to help solve some of society’s toughest challenges — from eradicating disease and improving education to addressing the needs of our local communities. Our mission is to build a more inclusive, just, and healthy future for everyone. CZI and its Biohub Network supports the science and technology that will make it possible to help scientists cure, prevent, or manage all diseases by the end of this century. Achieving our mission will only be possible if scientists are able to better understand human biology. To that end, we have identified four grand challenges that will unlock the mysteries of the cell and how cells interact within systems — paving the way for new discoveries that will change medicine in the decades that follow. Our work in science is focused on doing fundamental research to better understand human biology and building the tools and technology that move science forward to prevent disease and get to cures faster. Join us in accelerating science.